PReS-FINAL-2128: Quality of life and psychosocial aspects in juvenile localized scleroderma (JLS): a cross-sectional study in 40 patients

Introduction JLS is a chronic, autoimmune disease, characterized by skin and subcutaneous tissues fibrosis, which can extend to underlying tissues up to muscle and bone. JLS can cause a poor quality of life and psychosocial and behavioural problems in affected children particularly when severe deformities such as face asymmetry, joint contractures, and growth disturbances of limbs develop. To date, quality of life and psychological aspects in JLS have been poorly investigated, often with contrasting findings.